Cirrhosis is a disease that may result from several liver diseases or conditions. The diseases and conditions (such as hepatitis or chronic alcoholism) that lead to cirrhosis typically injure and kill liver cells, and the inflammation and repair that is associated with the dying liver cells causes scar tissue to form. The scar tissue blocks the flow of blood through the liver and eventually prevents the liver from functioning properly.

Cirrhosis is the seventh leading cause of death by disease, and it is estimated that 27,000 Americans die of cirrhosis each year.

The liver is the largest internal organ in the human body, and it plays a major role in metabolism and digestion. It also has a number of other functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis and detoxification. It’s no wonder that liver disease can cause widespread disruption of body function.

In the beginning stages of cirrhosis, there may not be any symptoms. As the disease worsens, symptoms may include:

Loss of appetite

Lack of energy (fatigue) which may be debilitating

Weight loss or sudden weight gain

Easy bruising from decreased production of blood clotting factors by the diseased liver

Yellowing of skin or the whites of eyes (jaundice)

Itchy skin due to bile products deposited in the skin

Fluid retention (edema) and swelling in the ankles, legs and abdomen

A brownish or orange tint to the urine

Gallstones if cirrhosis prevents bile from reaching the gallbladder, gallstones may develop

Portal hypertension, where the normal flow of blood from the intestines and spleen to the liver is slowed

Blood in the stool that may indicate bleeding in the digestive system

Confusion, delirium, personality changes, or hallucinations from buildup of drugs or toxins in the blood, which then affect the brain

Fever

Cirrhosis is generally irreversible once it occurs. Treatment of cirrhosis includes 1) preventing further damage to the liver, 2) treating the complications, 3) preventing liver cancer or detecting it early, and 4) liver transplantation.

Immediate things you can do at home if you suspect you have cirrhosis are as follows:

Stop drinking alcohol. If you stop all alcohol intake, you may slow the disease.

Avoid medications that may be harmful to your liver, such as acetaminophen (Tylenol), or your kidneys, such as ibuprofen (Advil, etc).

Cut down on salt if you are experiencing fluid retention.

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